Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 111
interventional 71
Observational 39
Registry 1

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 53
Drug|placebo 9
Other 2
Behavioral|Drug|Other 1
Biological 1
Biological|Device 1
Biological|Drug 1
Dietary Supplement 1
Drug|Genetic 1
Drug|Other 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 11
United Kingdom 10
India 9
France 7
NA 7
Spain 3
Australia 2
Japan 2
Korea, Republic of 2
Austria|France|Germany|Italy|Poland|Spain|Sweden|United Kingdom 1
Belgium|France|Germany|Italy|Slovakia|Switzerland|Turkey 1
Belgium|Germany 1
Belgium|Netherlands 1
Belgium|Switzerland 1
Canada 1
France|United Kingdom 1
Italy 1
Korea, Republic of|Peru|Russian Federation 1
Netherlands 1
Singapore 1
Taiwan 1
United States|Argentina|Australia|Belgium|Brazil|Canada|Chile|China|Egypt|France|Germany|Hungary|India|Israel|Italy|Korea, Republic of|Malaysia|Mexico|Netherlands|New Zealand|Poland|Russian Federation|Spain|Switzerland|Thailand|Turkey 1
United States|Argentina|Australia|Belgium|Brazil|Canada|Chile|Egypt|France|Germany|India|Israel|Korea, Republic of|Lebanon|Mexico|Poland|Russian Federation|South Africa|Thailand 1
United States|Australia|Belgium|Brazil|Canada|Czech Republic|France|Germany|Greece|India|Italy|Korea, Republic of|Netherlands|Peru|Poland|Portugal|Russian Federation|Singapore|Spain|Switzerland|Taiwan|Thailand|Turkey|United Kingdom 1
United States|Australia|Belgium|France|Germany|Hungary|Ireland|Israel|Italy|Luxembourg|Netherlands|Spain|Sweden|Switzerland|United Kingdom 1
United States|Austria|Germany|Netherlands|Spain|United Kingdom 1
United States|Belgium|Spain 1

Sites per Study

Site_count Study_Count
1 47
2 4
3 1
4 4
6 3
7 1
8 1
13 1
15 2
18 1
23 1
30 1
74 1
97 1
107 2

Phase

Phase Study_Count
Phase 2 17
Phase 3 17
Phase 1 14
Phase 2/Phase 3 10
Phase 4 8
N/A 5

Number of Arms

Number_of_Arms Count_of_Studies
1 17
2 28
3 3
4 4
6 1
10 2
18 1
NA 15

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 7.0 12.00000 11.00 21.0 10.0000 7.00
1st Qu. 29.0 21.00000 30.00 34.5 121.0000 23.00
Median 100.0 35.00000 52.50 71.0 224.0000 30.00
Mean 186.4 37.28571 85.75 99.1 301.9412 42.75
3rd Qu. 320.0 45.75000 112.50 137.5 459.0000 48.25
Max. 476.0 76.00000 326.00 320.0 800.0000 100.00

Trial Group Type

group_type Group_Count
Experimental 89
Placebo Comparator 26
Active Comparator 21
NA 15
Other 5
No Intervention 1

Intervention Model

intervention_model Study_Count
Parallel Assignment 32
Single Group Assignment 27
NA 8
Crossover Assignment 3
Sequential Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 53
Prevention 6
Diagnostic 3
Other 3
Supportive Care 3
NA 3

Observational Studies

Studies by Country

Country Study_Count
Germany 9
France 5
United States 5
Austria|Germany 3
Netherlands 3
Belgium 2
NA 2
Spain 2
Switzerland 2
China 1
Denmark 1
Egypt 1
Sweden 1
Taiwan 1
United Kingdom 1

Sites per Study

Site_count Study_Count
1 25
2 3
3 1
4 2
6 1
8 1
9 1
11 1
12 2
22 1
27 1

Enrollment Metrics

Measure Observational
Min 24.0000
1st Qu 85.0000
Median 200.0000
Mean 185.7027
3rd Qu 221.0000
Max 700.0000

Observation Model

observational_model Study_Count
Cohort 23
Case-Only 7
Case-Control 4
Case Control 2
NA 2
Other 1

Time Perspective

time_perspective Study_Count
Prospective 28
Retrospective 8
Cross-Sectional 2
NA 1

Registries

Studies by Country

Country Study_Count
Germany|Netherlands 1

Sites per Study

Site_count Study_Count
2 1

Enrollment Metrics

Measure Registries
Min 220
1st Qu 220
Median 220
Mean 220
3rd Qu 220
Max 220

Registry Model

observational_model Study_Count
Case-Only 1

Time Perspective

time_perspective Study_Count
Prospective 1

Follow-up

target_duration Study_Count
4 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03816176 A Study to Evaluate Isavuconazonium Sulfate for the Treatment of Invasive Aspergillosis (IA) or Invasive Mucormycosis (IM) in Pediatric Participants https://ClinicalTrials.gov/show/NCT03816176 Active, not recruiting Astellas Pharma Inc 2022-02-28
NCT03378479 Posaconazole for the Prevention of Influenza-associated Aspergillosis in Critically Ill Patients https://ClinicalTrials.gov/show/NCT03378479 Recruiting Universitaire Ziekenhuizen Leuven 2019-03-30
NCT03340597 Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects https://ClinicalTrials.gov/show/NCT03340597 Completed F2G Ltd. 2018-04-13
NCT02440009 A Randomized Trial of Itraconazole in Acute Stages of Allergic Bronchopulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT02440009 Recruiting Postgraduate Institute of Medical Education and Research 2018-12-31
NCT03133299 A Study Evaluating Vitamin D in Allergic Bronchopulmonary Aspergillosis Complicating Asthma https://ClinicalTrials.gov/show/NCT03133299 Completed Postgraduate Institute of Medical Education and Research 2018-06-30
NCT03059992 Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment https://ClinicalTrials.gov/show/NCT03059992 Recruiting Scynexis, Inc. 2021-09-30
NCT02955966 PET/CT Guided Antifungal Stewardship in Invasive Pulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT02955966 Recruiting Assistance Publique - Hôpitaux de Paris 2020-08-31
NCT02851680 Interest of ß 1-3 D Glucan Assays in Screening for the Onset of Invasive Aspergillosis in Neutropenic Patients With Acute Leukaemia. https://ClinicalTrials.gov/show/NCT02851680 Completed Centre Hospitalier Universitaire Dijon 2015-05-31
NCT02737371 Multiple Ascending Oral Dose Study of F901318 in Healthy Subjects https://ClinicalTrials.gov/show/NCT02737371 Completed F2G Ltd. 2017-05-22
NCT02730442 Study of Potential for Interaction of Fluconazole With F901318 https://ClinicalTrials.gov/show/NCT02730442 Completed F2G Ltd. 2016-06-30
NCT02715570 A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of PC945 https://ClinicalTrials.gov/show/NCT02715570 Completed Pulmocide Ltd 2018-04-27
NCT02680808 Evaluation of the Potential for Cytochrome P450 3A4 Inhibition by F901318 Using Oral Midazolam as a Probe https://ClinicalTrials.gov/show/NCT02680808 Completed F2G Ltd. 2016-06-30
NCT02631954 Phase I Clinical Trial for Comparison of Pharmacokinetic Characteristics of Vorico Injection 200mg(Voriconazole) and Vfend® IV 200mg for Single Dose Crossover Intravenous Infusion in Healthy Volunteers https://ClinicalTrials.gov/show/NCT02631954 Completed Chong Kun Dang Pharmaceutical 2015-10-31
NCT02394483 Single Ascending Oral Dose Study of F901318 https://ClinicalTrials.gov/show/NCT02394483 Completed F2G Ltd. 2016-09-30
NCT02342574 F901318 Multiple Ascending Dose Study https://ClinicalTrials.gov/show/NCT02342574 Completed F2G Ltd. 2016-09-30
NCT02273661 Evaluation of a Therapeutic Strategy Including Nebulised Liposomal Amphotericin B (Ambisome®) in Maintenance Treatment of Allergic Bronchopulmonary Aspergillosis (Cystic Fibrosis Excluded). https://ClinicalTrials.gov/show/NCT02273661 Completed Poitiers University Hospital 2019-06-28
NCT02180165 Assessing the Safety and Efficacy of MK-5592 (Posaconazole) in Japanese Participants With Fungal Infection (MK-5592-101) https://ClinicalTrials.gov/show/NCT02180165 Completed Merck Sharp & Dohme Corp. 2018-01-24
NCT02142153 F901318 Single Ascending Dose Study in Healthy Male Volunteers https://ClinicalTrials.gov/show/NCT02142153 Completed F2G Ltd. 2014-10-31
NCT01857479 A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT01857479 Completed Postgraduate Institute of Medical Education and Research 2015-06-30
NCT01782131 A Study of the Safety and Efficacy of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis (MK-5592-069) https://ClinicalTrials.gov/show/NCT01782131 Completed Merck Sharp & Dohme Corp. 2019-07-10
NCT01621321 Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT01621321 Completed Postgraduate Institute of Medical Education and Research 2016-04-30
NCT01615809 Nebulized Amphotericin B Lipid Complex in Invasive Pulmonary Aspergillosis in Paediatric Patients With Acute Leukaemia https://ClinicalTrials.gov/show/NCT01615809 Completed Fundació Sant Joan de Déu 2013-07-31
NCT01576315 ATCF (Azole Therapy in Cystic Fibrosis) https://ClinicalTrials.gov/show/NCT01576315 Completed Rennes University Hospital 2015-10-31
NCT01383993 Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To Less Than 15 Years Old Who Are At High Risk For Systemic Fungal Infection https://ClinicalTrials.gov/show/NCT01383993 Completed Pfizer 2013-05-31
NCT01321827 Monotherapy of Itraconazole Versus Prednisolone in Allergic Bronchopulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT01321827 Completed Postgraduate Institute of Medical Education and Research 2013-03-31
NCT04227483 Deflazacort vs. Prednisolone in Acute-stage ABPA https://ClinicalTrials.gov/show/NCT04227483 Recruiting Postgraduate Institute of Medical Education and Research 2022-01-14
NCT04108962 Benralizumab in the Treatment of Patients With Severe Asthma With ABPA https://ClinicalTrials.gov/show/NCT04108962 Recruiting Baylor Research Institute 2022-04-30
NCT03920527 Six Months Versus 12 Months of Oral Itraconazole Therapy for Management of Treatment naïve Subjects With CPA https://ClinicalTrials.gov/show/NCT03920527 Recruiting Postgraduate Institute of Medical Education and Research 2021-01-31
NCT03828773 PTX3-targeted Antifungal Prophylaxis https://ClinicalTrials.gov/show/NCT03828773 Recruiting Centre Hospitalier Universitaire Vaudois 2022-07-31
NCT03731169 CYP2C19 Genotype-Specific Dosing Plus TDM on Reaching Therapeutic Voriconazole Blood Levels https://ClinicalTrials.gov/show/NCT03731169 Recruiting University Health Network, Toronto 2019-06-30
NCT03717623 Posaconazole Pharmacokinetics in Patients Receiving Chemotherapy or Stem Cell Transplants https://ClinicalTrials.gov/show/NCT03717623 Recruiting Melbourne Health 2020-06-30
NCT03672292 Study to Evaluate the Safety and Efficacy of the Coadministration of Ibrexafungerp (SCY-078) With Voriconazole in Patients With Invasive Pulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT03672292 Recruiting Scynexis, Inc. 2020-09-30
NCT03656081 Chronic Pulmonary Aspergillosis and Ambisome Aerosol With Itraconazole https://ClinicalTrials.gov/show/NCT03656081 Recruiting Poitiers University Hospital 2021-06-30
NCT01259336 Efficacy Of Itraconazole In Chronic Cavitary Pulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT01259336 Completed Postgraduate Institute of Medical Education and Research 2011-06-30
NCT01222273 Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT01222273 Completed University of Pittsburgh 2013-09-30
NCT01165320 A Study of Caspofungin (MK-0991) in Japanese Children and Adolescents With Documented Candida or Aspergillus Infections (MK-0991-074) https://ClinicalTrials.gov/show/NCT01165320 Completed Merck Sharp & Dohme Corp. 2013-09-17
NCT01080651 Influence of Drug-drug Interactions on the Pharmacokinetics (PK) of Voriconazole https://ClinicalTrials.gov/show/NCT01080651 Completed Seoul National University Hospital 2009-03-31
NCT00974766 Trial on the Efficacy and Safety of Two Different Glucocorticoid Dose Regimens in Allergic Bronchopulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT00974766 Completed Postgraduate Institute of Medical Education and Research 2011-03-31
NCT00940017 A Study To Assess The Anidulafungin And Voriconazole Concentration In Lung Following Intravenous Administration In Healthy Subjects https://ClinicalTrials.gov/show/NCT00940017 Completed Pfizer 2008-10-31
NCT04267497 Nebulised Liposomal Amphotericin for Invasive Pulmonary Aspergillosis (NAIFI01 Study) https://ClinicalTrials.gov/show/NCT04267497 Recruiting Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal 2022-06-30
NCT02808741 Evaluation of Immediate Release Tablet https://ClinicalTrials.gov/show/NCT02808741 Completed F2G Ltd. 2016-11-30
NCT01710930 Protocol TARC-ABPA https://ClinicalTrials.gov/show/NCT01710930 Completed Nantes University Hospital 2017-09-21
NCT04218851 Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104) https://ClinicalTrials.gov/show/NCT04218851 Recruiting Merck Sharp & Dohme Corp. 2023-02-06
NCT04229303 Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects https://ClinicalTrials.gov/show/NCT04229303 Recruiting Zambon SpA 2020-07-31
NCT00784368 A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection https://ClinicalTrials.gov/show/NCT00784368 Completed Janssen Pharmaceutical K.K. 2009-04-30
NCT00717860 A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED) https://ClinicalTrials.gov/show/NCT00717860 Completed Merck Sharp & Dohme Corp. 2010-07-31
NCT00647907 A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal Infections https://ClinicalTrials.gov/show/NCT00647907 Completed Pfizer NA
NCT00634049 Isavuconazole in the Treatment of Renally Impaired Aspergillosis and Rare Fungi https://ClinicalTrials.gov/show/NCT00634049 Completed Astellas Pharma Inc 2014-01-03
NCT00531479 Anidulafungin Plus Voriconazole Versus Voriconazole For The Treatment Of Invasive Aspergillosis https://ClinicalTrials.gov/show/NCT00531479 Completed Pfizer 2011-04-30
NCT00501098 Prophylaxis of Fungal Invasive Infections in Leukemia https://ClinicalTrials.gov/show/NCT00501098 Completed Northern Italy Leukemia Group 2008-12-31
NCT00412893 Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis https://ClinicalTrials.gov/show/NCT00412893 Completed Astellas Pharma Inc 2013-03-28
NCT00404092 Caspofungin Maximum Tolerated Dose in Patients With Invasive Aspergillosis https://ClinicalTrials.gov/show/NCT00404092 Completed University of Cologne 2009-10-31
NCT00391014 Nebulized Liposomal Amphotericin B Ambisome for Prophylaxis of Invasive Pulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT00391014 Completed PETHEMA Foundation 2008-12-31
NCT00361517 To Determine Whether Galactomannan Test Will Help to Detect Fungal Infections Early and Hence Start Treatment Early https://ClinicalTrials.gov/show/NCT00361517 Completed Singapore General Hospital 2007-10-30
NCT00334412 COMBISTRAT: AmBisome® in Combination With Caspofungin for the Treatment of Invasive Aspergillosis https://ClinicalTrials.gov/show/NCT00334412 Completed Gilead Sciences NA
NCT00263315 Inhalation of Liposomal Amphotericin B to Prevent Invasive Aspergillosis https://ClinicalTrials.gov/show/NCT00263315 Completed Erasmus Medical Center NA
NCT00163722 A Multicentre Randomised Controlled Trial Comparing Two Strategies for the Diagnosis of Invasive Aspergillosis in High-risk Haematology Patients https://ClinicalTrials.gov/show/NCT00163722 Completed Bayside Health 2011-01-31
NCT00159822 Voriconazole For Chronic Bronchopulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT00159822 Completed Pfizer 2008-12-31
NCT00158730 Study Safety/Efficacy of AmBisome Loading Dose Regimen Versus Standard AmBisome Regimen for Initial Treatment https://ClinicalTrials.gov/show/NCT00158730 Completed Gilead Sciences NA
NCT00110045 Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant https://ClinicalTrials.gov/show/NCT00110045 Completed European Organisation for Research and Treatment of Cancer - EORTC 2008-03-31
NCT00003031 Comparison of Voriconazole and Amphotericin B in Treating Patients With Aspergillosis https://ClinicalTrials.gov/show/NCT00003031 Completed European Organisation for Research and Treatment of Cancer - EORTC 2000-10-31
NCT00082524 Documented Candida or Aspergillus Infections in Pediatric Patients (0991-043) https://ClinicalTrials.gov/show/NCT00082524 Completed Merck Sharp & Dohme Corp. 2007-07-31
NCT00076869 MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037) https://ClinicalTrials.gov/show/NCT00076869 Completed Merck Sharp & Dohme Corp. 2004-09-30
NCT00059878 Voriconazole With or Without Interferon Gamma in Treating Patients With Aspergillosis or Other Fungal Infections https://ClinicalTrials.gov/show/NCT00059878 Completed National Cancer Institute (NCI) NA
NCT00005912 Voriconazole to Prevent Systemic Fungal Infections in Children https://ClinicalTrials.gov/show/NCT00005912 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001937 Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients https://ClinicalTrials.gov/show/NCT00001937 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001810 An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections https://ClinicalTrials.gov/show/NCT00001810 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001646 Voriconazole vs. Amphotericin B in the Treatment of Invasive Aspergillosis https://ClinicalTrials.gov/show/NCT00001646 Completed National Institutes of Health Clinical Center (CC) NA
NCT00037206 A Safety & Effectiveness Study of Intravenous Anidulafungin With AmBisome® for Treatment of Invasive Aspergillosis (IA). https://ClinicalTrials.gov/show/NCT00037206 Completed Pfizer NA
NCT00036166 Study of FK463 for the Treatment of Invasive Aspergillosis https://ClinicalTrials.gov/show/NCT00036166 Completed Astellas Pharma Inc 2002-01-31
NCT00005668 A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of Aspergilloma https://ClinicalTrials.gov/show/NCT00005668 Completed National Institute of Allergy and Infectious Diseases (NIAID) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03121235 PCR Based Detection of Azole Resistance in A. Fumigatus to Improve Patient Outcome. https://ClinicalTrials.gov/show/NCT03121235 Recruiting Erasmus Medical Center 2020-12-31
NCT03067350 Influence of a Combined Pharmacogenetic Score on Through Plasma Voriconazole Concentrations in Haematological Patients https://ClinicalTrials.gov/show/NCT03067350 Completed University Hospital, Grenoble 2019-01-31
NCT01614145 Diagnostic Performance of an Aspergillus-specific Nested PCR Assay in Cerebrospinal Fluid Samples https://ClinicalTrials.gov/show/NCT01614145 Enrolling by invitation Heidelberg University 2020-12-31
NCT02900430 Invasives Aspergillosis in Acute Myeloid Leukemia https://ClinicalTrials.gov/show/NCT02900430 Completed University Hospital, Brest 2015-12-31
NCT02853175 Lung MRI and Allergic Broncho-pulmonary Aspergillosis in Cystic Fibrosis https://ClinicalTrials.gov/show/NCT02853175 Completed Hôpital Haut-Lévêque 2018-05-31
NCT03643185 Cytokine Profile of Allergic Bronchopulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT03643185 Recruiting Shanghai Pulmonary Hospital, Shanghai, China 2021-05-04
NCT02106117 Exhaled Breath Analysis in the Early Detection of Aspergillosis https://ClinicalTrials.gov/show/NCT02106117 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2017-03-31
NCT02104479 Diagnostic Accuracy of Pleural Effusion Aspergillosis Biomarker Testing https://ClinicalTrials.gov/show/NCT02104479 Enrolling by invitation Heidelberg University 2020-12-31
NCT02058316 Bronchoalveolar Lavage Lateral-Flow Device Test for Invasive Pulmonary Aspergillosis: a Multicenter Study https://ClinicalTrials.gov/show/NCT02058316 Recruiting Medical University of Graz 2019-07-31
NCT01902030 Evaluation of Performance of An Aspergillus PCR in Tissue and Pleural Effusion Samples of Immunocompromised Patients https://ClinicalTrials.gov/show/NCT01902030 Enrolling by invitation Heidelberg University 2020-12-31
NCT01866020 Diagnosis of Invasive Pulmonary Aspergillosis (IPA) in Critically Ill Patients https://ClinicalTrials.gov/show/NCT01866020 Completed Universitätsklinikum Hamburg-Eppendorf 2014-07-31
NCT01695512 Diagnostic Study of Combined Biomnarker Testing in Bronchoalveolar Lavage Samples of Immunocompromised Patients https://ClinicalTrials.gov/show/NCT01695512 Enrolling by invitation Heidelberg University 2020-12-31
NCT01695499 Diagnostic Study of Biomarkers in BAL of ICU Patients With Lung Infiltrates https://ClinicalTrials.gov/show/NCT01695499 Enrolling by invitation Heidelberg University 2020-12-31
NCT01617759 Aspergillus-specific PCR Assay in Cerebrospinal Fluid Samples for Detection of Central Nervous System Aspergillosis https://ClinicalTrials.gov/show/NCT01617759 Enrolling by invitation Heidelberg University 2020-12-31
NCT01448226 Diagnosing Invasive Aspergillosis by Polymerase Chain Reaction (PCR) Based Investigation of Bronchoalveolar Lavage Samples During Antifungal Therapy https://ClinicalTrials.gov/show/NCT01448226 Completed Heidelberg University 2011-01-31
NCT01430663 Diagnosing Pulmonary Aspergillosis in Patients With Hematological Malignancies: A Multicentre Prospective Evaluation of an Aspergillus PCR Assay and a Galactomannan ELISA in Bronchoalveolar Lavage Samples https://ClinicalTrials.gov/show/NCT01430663 Completed Heidelberg University 2011-02-28
NCT01395446 Application of an Electronic Nose in the Early Detection of ASpergillosis https://ClinicalTrials.gov/show/NCT01395446 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2012-07-31
NCT04431804 Silver Nanoparticle Effect on Fungi https://ClinicalTrials.gov/show/NCT04431804 Recruiting Assiut University 2020-07-11
NCT04358419 Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by Use of Biomarkers in Exhaled Breath Condensate https://ClinicalTrials.gov/show/NCT04358419 Recruiting Aalborg University Hospital 2021-12-31
NCT04232956 Invasive Pulmonary Aspergillosis and Severe Influenza https://ClinicalTrials.gov/show/NCT04232956 Completed University Hospital, Brest 2018-11-05
NCT04172610 Prevalence of Influenza RelAted Invasive Aspergillosis https://ClinicalTrials.gov/show/NCT04172610 Recruiting Karolinska University Hospital 2020-04-30
NCT04077697 Clinical and Prognostic Comparisons Between Invasive Pulmonary Aspergillosis With or Without Invasive Tracheobronchitis During Severe Influenza: a Retrospective Multicenter Cohort Study. https://ClinicalTrials.gov/show/NCT04077697 Completed Centre Hospitalier Universitaire, Amiens 2019-07-16
NCT03827694 Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections https://ClinicalTrials.gov/show/NCT03827694 Recruiting Duke University 2022-12-31
NCT03748069 Influenza Associated Aspergillosis In-depth Investigation https://ClinicalTrials.gov/show/NCT03748069 Recruiting Universitaire Ziekenhuizen Leuven 2021-04-30
NCT03641131 Ampholipad Real-World Data in Taiwan https://ClinicalTrials.gov/show/NCT03641131 Completed Taiwan Liposome Company 2019-01-02
NCT03443336 Azole-resistance in Aspergillus https://ClinicalTrials.gov/show/NCT03443336 Active, not recruiting University Hospital, Basel, Switzerland 2019-06-30
NCT01247142 Evaluation of Exhaled Breath Condensate in the Diagnosis of Invasive Pulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT01247142 Completed Universitaire Ziekenhuizen Leuven 2014-07-31
NCT01178177 Radiologic Features of Invasive Pulmonary Aspergillosis https://ClinicalTrials.gov/show/NCT01178177 Completed Asan Medical Center 2010-02-28
NCT01128907 Galactomannan Antigen in Bronchoalveolar Lavage in the Diagnosis of Invasive Aspergillosis in Neutropenic Patients https://ClinicalTrials.gov/show/NCT01128907 Completed Fundació Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau 2012-12-31
NCT01040156 Antimycotic Prophylaxis in Pediatric Patients Following Allogeneic Stem Cell Transplantation https://ClinicalTrials.gov/show/NCT01040156 Completed University Children’s Hospital Tuebingen 2009-12-31
NCT00923832 Early Molecular Detection for the Improved Diagnosis of Invasive Pulmonary Aspergillosis and Invasive Pulmonary Zygomycosis https://ClinicalTrials.gov/show/NCT00923832 Completed National Institutes of Health Clinical Center (CC) NA
NCT00906568 Evaluation of Bronchial Inflammation in Allergic Bronchopulmonary Aspergillosis (ABPA) https://ClinicalTrials.gov/show/NCT00906568 Completed Johann Wolfgang Goethe University Hospital 2010-05-31
NCT00854607 An Observational Study of Fungal Biomarkers (MK-0000-089) https://ClinicalTrials.gov/show/NCT00854607 Completed Merck Sharp & Dohme Corp. 2011-06-30
NCT00816088 Diagnostic and Management Strategies for Invasive Aspergillosis https://ClinicalTrials.gov/show/NCT00816088 Completed King’s College Hospital NHS Trust 2011-12-31
NCT01386437 Natural History of Individuals With Immune System Problems That Lead to Fungal Infections https://ClinicalTrials.gov/show/NCT01386437 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00585364 Mechanisms of Immune Tolerance and Inflammation in Patients With Cystic Fibrosis With ABPA https://ClinicalTrials.gov/show/NCT00585364 Completed University of Pittsburgh 2010-12-31
NCT00473252 Surveillance of Fungal Infections During Construction Activity https://ClinicalTrials.gov/show/NCT00473252 Completed University Hospital Inselspital, Berne 2009-07-31
NCT00388167 Acetato de Caspofungin (Cancidas®) in the Treatment of Fungal Infection https://ClinicalTrials.gov/show/NCT00388167 Completed PETHEMA Foundation NA
NCT00177827 Voriconazole Prophylaxis Against Aspergillosis in Lung Transplant Recipients https://ClinicalTrials.gov/show/NCT00177827 Completed University of Pittsburgh NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03221075 Clinical Implications of Azole-Resistant Aspergillosis in Hematological Malignancy https://ClinicalTrials.gov/show/NCT03221075 Recruiting University Hospital of Cologne 2020-06-01